Virginia State Police named the person who died in the crash as 22-year-old James Lineberry, of Hillsville.
Troopers believe Lineberry was driving a 2000 Pontiac Sunfire north on Route 52, when the car crossed the center line, and hit a 1999 Chevrolet Trailblazer going south head-on. A 2003 Toyota sedan then rear-ended the Trailblazer.
Investigators say Lineberry was not wearing a seatbelt.
EMTs took the driver and passenger from the Trailblazer to a hospital for treatment of non-serious injuries. The Toyota's driver luckily was not hurt.
State Police are still trying to figure out what caused the crash.
Virginia State Police are investigating a deadly crash that took place in Carroll County Tuesday afternoon.
According to State Police spokeswoman Corinne Geller, the crash happened on Route 52 in the northern part of Cana, around 2:44 p.m.
One person died in the crash.
The collision blocked all lanes of Route 52 for more than an hour.
Geller said the investigation is ongoing.